Malaria

Version: November 2025

Introduction

Malaria is a life-threatening disease caused by Plasmodium parasites, transmitted to humans through the bites of infected female Anopheles mosquitoes. It is characterized by symptoms such as fever, chills, headache, and muscle aches, often leading to severe complications if untreated. Predominantly affecting tropical and subtropical regions, malaria is a major public health concern in sub-Saharan Africa, South Asia, and parts of Latin America. Effective prevention strategies include mosquito control measures, use of insecticide-treated bed nets, and prophylactic antimalarial medications. Advances in diagnostics and treatment have improved patient outcomes, but efforts for eradication continue globally.

Highlights

  1. Consistent Resurgence in Cases: From mid-2019, a steady increase in malaria cases is observed, particularly sharp from mid-2025, reaching over 400 cases in some months, up from mid-2021’s declining trend.

  2. Fluctuations in Mortality Rates: While deaths vary, peaks are noted, such as four in November 2024, despite low mortality in 2025. This suggests improvements in treatment and recovery.

  3. Seasonal Variations: Higher case counts are evident from May to September each year, indicating potential seasonal influences or environmental factors facilitating transmission.

  4. Recent Increase in Burden: The upward trend in both cases and deaths needs immediate addressing with strengthened public health measures and enhanced anti-malaria campaigns.

Analysis

Cases Analysis

The malaria data from the Chinese mainland reveals a fluctuating pattern in reported cases from November 2015 to November 2025. Initially, there was a peak in cases, notably in May and June 2016, with over 350 cases. However, the general trend until 2019 saw declines with seasonal variations, commonly peaking at year’s start. A dramatic reduction occurred in 2020, coinciding with the COVID-19 pandemic, possibly due to restrictive measures impacting vector movement and transmission, with cases dropping to as low as 40.

Post-2020, cases began rising again, marked by an increase around mid-2022 and continued increases into 2025. The resurgence saw cases reach over 400 in mid-2025. Despite fluctuations in case numbers, deaths remained relatively low, suggesting effective healthcare and control measures were in place to manage the complications of malaria. This stability in mortality rates amidst rising infections might reflect improved treatment and preventive strategies.

The overall change in malaria case trends could be influenced by factors such as climate, vector habitat changes, and international travel. While the resurgence indicates some level of vulnerability, the relatively stable and low mortality figures point towards a well-managed health response system mitigating the fatalities despite increasing case counts.

Deaths Analysis

The mortality trend in malaria cases reported from the Chinese mainland between November 2015 and November 2025 reflects an intriguing, albeit fluctuating, pattern. Initial observations denote sporadic mortality rates with relatively higher peaks seen within the initial years of observation, specifically during the years 2016 and 2019, where monthly deaths reached as many as four per month. However, the data from the subsequent years demonstrate a generally declining trend in both malaria case reports and associated fatalities. Notably, from 2020 onwards, there is a significant drop in the number of reported cases and consequently reduced mortality, with multiple months reflecting zero deaths. During this period, the correlation between the number of cases and the deaths became less direct, suggesting possible advancements in healthcare access or treatments.

Interestingly, beginning in 2023, there seems to be a resurgence in the number of reported malaria cases, yet the mortality rates do not escalate to previous levels. This could imply improvements in case management strategies that effectively decouple case prevalence from mortality impact. This pattern persists into 2025, where despite the rise in case numbers reaching over 400 per month, mortality remains marginal, suggesting effective disease control mechanisms have been consistently implemented despite an apparent rise in transmission rates. Overall, the data reflects considerable progress in mitigating malaria-related mortality, showcasing improved public health responses and possibly advances in therapeutic interventions over the observed timeframe.

Source Data

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